Out of 400+ applications, we've selected 180+ PIC semifinalists. These ventures represent all 13 Harvard schools and are one step closer to winning a share of $500,000+ in Bertarelli Foundation funding.
2026
President’s Innovation Challenge
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All
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Accounting
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Advertising
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Aerospace and Defense
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Agriculture
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AI / Machine Learning
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Aid and Relief
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Architecture, Construction, and Engineering
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Arts and Culture
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Aviation and Aerospace
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B2B/Enterprise or High Tech
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Bioinformatics
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Biotech / Life Sciences
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Biotech and Life Sciences
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Biotech and Therapeutics
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Business Services
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Childhood Development
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Climate & CleanTech
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Climate and Sustainability
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Co-founder dynamics
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Consumer Products and Packaged Goods
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Consumer Products/Services
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Cultural Entrepreneurship
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Defense, Military, and Space
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Diagnostics
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Digital Health
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Diversity,
Equity, Inclusion, and Belonging
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Diversity, Equity, Inclusion, and Belonging
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E-commerce & Consumer
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Ecommerce
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EdTech & Learning
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Education and Learning
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Education Technology
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Electronics and Hardware
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Employment, Recruiting, and Workforce Development
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Energy, Oil, and Renewables
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Energy, Oil, Renewables, and Environment
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Entertainment
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Fashion, Beauty, and Retail
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Fashion, Beauty, Apparel, and Retail
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Finance
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Finance and Insurance
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Fitness and Sports
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Food & Agriculture
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Food and Beverages
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Gaming
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Gaming / Media / Entertainment
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Government and Civic Engagement
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Harvard Libraries / Research
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Healthcare
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Healthcare Delivery
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Hospitality and Tourism
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Insurance
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Insurance / InsurTech
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International Development
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Legal
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Legal (Startup/Immigration/IP)
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Life Sciences
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Marketing
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Marketing / Brand / Growth
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Media and Entertainment
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Media and Publishing
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Medical Devices and Hardware
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Mental Health
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Mentorship and youth development
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Music
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Personal Health and Wellness
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Personal Health, Wellness, and Sports
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Public Health and Global Health
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Real Estate / PropTech
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Real Estate and Housing
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Robotics & Automation
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Services
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Social Enterprise
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Software/App
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Space / Aerospace
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Technology
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Therapeutics
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Transportation and Logistics
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Travel, Tourism, and Hospitality
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Venture Capital
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Venture Capital / Investing
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Web3, Crypto, and NFTs
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Workforce / HR
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All
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Harvard Business School
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Harvard College
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Harvard Divinity School
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Harvard Extension School
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Harvard Faculty of Arts and Sciences
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Harvard Graduate School of Arts & Sciences
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Harvard Graduate School of Design
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Harvard Graduate School of Education
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Harvard John A. Paulson School of Engineering and Applied Sciences
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Harvard Kennedy School
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Harvard Kenneth C. Griffin Graduate School of Arts and Sciences
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Harvard Law School
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Harvard Medical School
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Harvard School of Dental Medicine
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Harvard T.H. Chan School of Public Health
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Harvard University
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HBS Business & Environment Initiative
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HBS Rock Center for Entrepreneurship
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I'm a post-doc
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John A. Paulson School of Engineering & Applied Sciences
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Non-Harvard Affiliate
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Other
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Radcliffe Institute for Advanced Study
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T.H Chan School of Public Health
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Mireta Urban Dynamics
Building biology-inspired AI tools to help developers plan more climate-resilient city networks.
![Mireta's founder presents in front of screens]()
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Mobile Memory
Harnessing AI and voice technology to detect early signs of cognitive impairment.
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Mobilio
Improving outdoor navigation for people who are blind through an AI-driven smartphone application with personalized audio guidance.
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Mona
Automating business capital access with AI agents.
![Mona venture photo]()
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MonitAir
The remote patient monitoring platform built for sleep medicine: helping practices monitor CPAP adherence, close care gaps, and get reimbursed for it.
![Man with dark blazer and white button-up.]()
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Morrownest
Breaking the cycle of generational trauma through a science-based approach that builds parent strengths and fosters supportive homes where children can thrive.
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MotionEdge Labs
Delivering adaptive multi-agent coaching through wearables to understand micro-movements and provide world-class physical guidance anytime, anywhere.
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NanoDEX
Accelerating drug discovery by leveraging nanopore technology to target previously challenging proteins.
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Nia Yetu
Strengthening families at risk of separation in Kenya and supporting youth aging out of orphanages to successfully reintegrate into the community.
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NuCyRNA Therapeutics
Redefining RNA-targeting therapeutics, starting in neurodegenerative diseases.
![Nucyrna team lead]()
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Omni | X
Building interoperable AI to coordinate aerial, terrestrial, nautical drones and humanoid robots for crisis response and national defense.
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Orchestra Research
Building a research copilot that lowers barriers to science and democratizes access for scientists and students worldwide.
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Overture Therapeutics
Creating better, healthier weight-loss intervention therapies for treating obesity and its co-morbidities by targeting emerging biological pathways.
![Russell Beckerman]()
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Oxyverse
Transforming neurocritical patient care by providing real-time, noninvasive brain monitoring through a wearable device.
![Oxyverse]()
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PACR
Building a social network for academics to share research, track impact, explore 500M+ papers, and use AI to engage with the global science ecosystem.
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PartyKeys
Developing a smart instrument that guides users in learning to play music.
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Patch
Transforming old smartphones into creative prototyping tools through hands-on STEM kits that help kids learn about technology and sustainability.
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PathCision Medicine
Developing tissue-informed precision therapeutics with superior delivery and efficacy for cancer and other complex diseases.
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Peri.ai
Building an agentic communication ecosystem that connects brands and content creators.
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Piassa.ai
An AI-native operating system for the built environment helping owners and operators automate workflows, reduce operating costs, and optimize asset performance.
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PieD
Developing an AI-powered wearable photonic device for at-home heart failure monitoring through real-time, multi-biomarker detection.
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PingCares
Developing a digital health platform that connects seniors and caregivers with real-time safety alerts, wellness tools, and daily support.
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PinkDetect
Empowering communities to fight breast cancer through education, early detection, and care access by combining cutting-edge technology with grassroots outreach.
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Pixel Pack
Automating digital design tasks with an AI tool that helps entrepreneurs create brand-ready visuals faster and at lower cost.
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Pochat.ai
Streamlining school administration with an AI assistant that automates workflows, reduces overhead, and supports educators and staff.
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PreguntaSalud
Advancing health equity by combining evidence-based health education with an AI-driven conversational assistant for Latin American communities.
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Process Intelligence and Dynamics
Building the world’s first agentic enterprise intelligence platform to solve complex operational and process challenges across manufacturing, inventory, and supply chains.
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Procure Bio
Engineering protein nanoparticles for targeted delivery of gene and protein therapeutics, advancing novel treatments for genetic diseases.
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Promakhos Therapeutics Inc.
Developing oral, non-immunosuppressive, small molecules to cure chronic inflammatory disorders.
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Qalam Health Solutions
Enabling surgeons to detect bone cancer cells in tissue margins with innovative tools during surgery to prevent cancer recurrence and optimize patient care.
![Qalam]()
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QLab
Accelerating dual-use technologies by helping Harvard and MIT teams build mission-ready solutions with guidance from Department of Defense and intelligence leaders.
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Quantum Skynet AI
Developing generative AI solutions to address critical gaps in personnel risk management screening.
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Rå
Scaling a smart-fridge retail platform that delivers curated wellness products to fitness spaces while providing brands with real-time consumer insights.
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REAcT
Delivering the first button-activated tourniquet that gives first responders confidence they’re saving lives correctly every time, eliminating the 70% failure rate.
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Reel Academy
Turning short-form videos into curriculum-aligned learning with tutor support and parent accountability to improve real student outcomes.
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Refine Technologies, Inc.
Developing AI peer review for research papers that provides reviewer-grade feedback in 30 minutes instead of months.
![Yann Calvo Lopez]()
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ReportCaddy
Using AI to manage and streamline regulatory compliance for energy infrastructure.
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ResearchGo
Matching students seeking research experience with graduate researchers who need help collecting data, sources, and field notes around the world.
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Retirees
Creating social communities for retirees to live longer, happier lives—both in person and online.
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Revolv
Turning organic waste into affordable animal feed and fertilizer that boosts farmer incomes and nutrition.
![Biruh Demilew]()
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Sabi Wise
Reimagining scalp and dandruff care with clean, effective products designed for every hair type and routine—working toward a flake-free future.
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Safe Space Connect, PLLC
Providing trauma-informed, culturally responsive counseling that creates a safe space for healing.
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SafeAI Health
Validating and monitoring AI tools in healthcare to ensure safety, equity, and trustworthy care by detecting bias, model drift, and failure risks.
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Sahas Labs
Helping OEMs, startups, and students build automation like LEGO with modular, AI-guided hardware that cuts build time so teams can focus on real innovation.
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Salience
Enabling high-bandwidth human–AI collaboration by allowing agents to understand user intent beyond text and command-based interactions.
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Sankofa Empowering Women in Ghana
Upcycling fast-fashion waste to deliver skills training, mentorship, and climate-conscious entrepreneurship opportunities for at-risk girls in Ghana.
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Scholar Spark
Providing premier research mentorship that helps talented students turn curiosity into credible research with guidance from expert academics and industry mentors.
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Scriptify
Scriptify helps pharmacies prevent medication complications for chronically ill patients—AI assists, but real clinicians guide every step.
![Aminu Osman Alem MD MPH]()
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smartSTAT
Modernizing hospital code carts with smart tracking and automated restocking to reduce waste, save time, and improve patient safety.
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Sole 1
Restoring mobility for people who cannot lift the front part of their foot using AI-powered robotic socks that assist with walking, prevent falls, and support nerve recovery.
![Sole 1 cofounders]()
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Spatially
Helping rural governments convert legacy zoning maps into digital GIS data for easier updates, transparent planning, and better development decisions.
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SPORO Health
Streamlining patient chart reviews for physicians, which takes them up to two hours per day.
![SPORO health]()
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StableCarbon LLC
Turning renewable energy and carbon outputs in emerging markets into finance-ready assets for global investors.
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Stage Zero Health
Transforming cancer prevention from reactive to proactive through personalized risk assessment and care navigation that enables earlier detection.
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Stenoa
The operating system for mission-critical care.
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Stock68, Inc.
Building an AI-powered all-in-one operating platform for the food distributors.
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Studio 3e8
Delivering a fully integrated hardware, software, and materials ecosystem for desktop metal 3D printing that makes professional-grade fabrication affordable, compact, and easy to use.
![studio 3e8]()
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Surna Technologies
Building sovereign AI infrastructure that enables emerging and frontier economies to build, deploy, and monitor their financial systems in real time.
![Hellen Siah Momoh]()
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Swik AI
Automating intake and pre-underwriting for non-bank lenders with fragmented data and manual workflows to enable faster credit decisions.
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TableIQ
Using computer-vision AI and POS data to increase server tips, improve service quality, grow tab sizes, and boost customer reviews.
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Talk You Never Got
Building an online sex education platform that leverages social media and digital learning to reach young adults in India.
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TeleOps
Enabling Uber-like robotic teleoperation through AI-native, bandwidth-efficient proprietary video streaming.
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The Black Roots
Creating individualized e-learning materials that support students pursuing healthcare careers by guiding them through prerequisite coursework.
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The Legacy Project, Inc.
Connecting college students with older adults nationwide through intergenerational storytelling programs.
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The NovaLand
Empowering neurodivergent children to escape digital overstimulation through interactive stories designed to regulate attention rather than overwhelm.
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The One Care
OneCare is a voice-first coordination layer that automates care logistics without requiring clinicians, non-clinicians or families to learn new software.
![CareCorgi]()
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The Wize Beverage Company PBC
Maximizing the value of coffee trees for farmers, roasters, and cafes by extending the useful life of coffee beans and monetizing coffee waste.
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Third Pole Solutions
Launching the Madad Electric Cookstove (MEC) Project to distribute 50,000 electric stoves in Northern Pakistan.
![Third Pole Solutions]()
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thragma
Making photos speak so stories are preserved, shared, and never forgotten.
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TP7
Creating mobile, dual-arm robots powered by physical-spatial AI that learn via natural language and work autonomously in high-mix, unstructured factories.
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TRACE
Using AI to transform product pages into marketplaces that connect shoppers in real time for resale, rental, and smarter buying decisions.
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Triality
Building the first continuous evidence engine for clinical trials that predicts event rates, feasibility, statistical power, and representation as evidence evolves.
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Truxtun
Offering coaching and retreats that blend performance science, community, and safe psychedelic access for veterans.
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Tummy
Helping IBD and IBS patients manage GI symptoms through a mobile app that delivers personalized, actionable dietary guidance.
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Unified Track
An AI-powered platform that helps high school counselors reduce absenteeism and improve graduation rates.
![Unified Track]()
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Upaya Health
Reimagining dermatology with plant-based, CBD-driven solutions that reduce inflammation and promote skin wellness.
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Valen VR
Bringing accessible VR into schools as a mental health resource to help students build emotional skills and develop mental maturity.
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Ventures Beyond Borders
Bridging the gap between refugee talent and opportunity by helping refugee entrepreneurs build scalable businesses.
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VoteNow
Making a mobile app that centralizes all dates, locations, and resources necessary to vote based off a user’s geofenced address.
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VScale
Helping startups raise capital, win clients, and build authority through strategic PR and proprietary virality systems and technology.
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Winko Solar
Delivering solar-powered oxygen to hospitals in Africa, with plans to expand globally.
![Akonkwa Mubagwa]()
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Youshine Education
Providing K–12 academic support and bridging information gaps through firsthand resources from a global school network.
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Zero Waste Carnic
Addressing the waste crisis in fragile Indian Ocean island communities by integrating sustainable Indigenous practices with technology-driven zero-waste solutions.
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Zolvay Systems, Inc.
Building enterprise AI capability infrastructure through a B2B platform and B2C certification that generates proprietary behavioral intelligence, with $1.2M in first-year ARR validated.
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Zone
Building EEG-enabled earbuds and an AI copilot to boost focus and executive function in adults with ADHD through real-time brain sensing.
