Ilios has built a chemistry platform to generate multi-functional, brain-penetrant small molecules rationally-designed to combat neurodegenerative diseases. Our first-in-class therapeutics are designed to synergistically address the three key mechanisms driving neurodegenerative diseases: oxidative stress, brain inflammation, and protein misfolding. Our first program is on Amyotrophic Lateral Sclerosis (ALS), with plans to expand our therapeutic pipeline to include treatments for Parkinson's and Alzheimer's diseases.